ELK Biotechnology V-ATPase H rabbit pAb
V-ATPase H rabbit pAb는 인간 및 생쥐 시료에서 V-ATPase H 단백질 검출용 다클론 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며 고순도 IgG 형태로 제공됩니다. 세포 내 소기관 산성화 관련 연구에 적합합니다.
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ELK Biotechnology V-ATPase H rabbit pAb
제품 개요
V-ATPase H rabbit pAb는 인간 ATP6V1H 유래 합성 펩타이드(AA 341–390)에 대해 생산된 다클론 항체로, 세포 내 소기관 산성화 및 단백질 분류 연구에 활용됩니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product Name | V-ATPase H rabbit pAb |
| Alternative Names | ATP6V1H; CGI-11; V-type proton ATPase subunit H; V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC: 1/100–1/300; ELISA: 1/20000; Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human ATP6V1H (AA range: 341–390) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kDa |
| GeneID (Human) | 51606 |
| Human Swiss-Prot No | Q9UI12 |
| Cellular Localization | Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein |
| Storage | -20°C, 1 year |
| Host Species | Rabbit |
Background
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (RefSeq, May 2012)
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