Thermo Fisher Scientific ATXN7L1 Monoclonal Antibody (OTI4B12), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ATXN7L1 (ataxin-7-like protein 1) is an 833 amino acid protein containing one SCA7 domain.
The ATXN7L1 gene is conserved in chimpanzee, canine, mouse, rat, and chicken, and maps to human chromosome 7q22.3.
Chromosome 7 encodes over 1,000 genes and constitutes about 5% of the human genome.
Mutations or deletions in this region have been linked to several genetic disorders, including osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia, and Shwachman-Diamond syndrome.
Deletion of part of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, characterized by mild intellectual disability, friendly demeanor, and distinctive facial features.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.