Thermo Fisher Scientific Noggin Polyclonal Antibody
Rabbit polyclonal antibody against human Noggin protein. Validated for Western blot with 1:1,000 dilution. Recognizes ~32 kDa Noggin band. Suitable for research use in developmental biology and BMP signaling studies.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues P(156) V L Y A W N D L G S R F W P(170) of the human Noggin (NOG) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2151684 |
Product Specific Information
PA1-4521 detects Noggin (NOG) in human samples.
The immunizing peptide sequence is 100% conserved in rat and mouse.
This antibody has been successfully used in Western blot procedures and specifically recognizes the ~32 kDa Noggin (NOG) protein.
The immunogen is a synthetic peptide corresponding to residues 156–170 of the human Noggin (NOG) protein.
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation.
Organ morphogenesis is initiated by downgrowth from epithelial stem cells, regulated by signals from WNT3A (stabilizing beta-catenin) and Noggin (a bone morphogenetic protein inhibitor).
Mutations in the Noggin gene are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by joint fusion defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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