Thermo Fisher Scientific OPRD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues T(361) P S D G P G G G A A A(372) of human DOR-1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OPRD1,uniProtId:P41143-1,ncbiNodeId:9606,antigenRange:361-372|362-372,antigenLength:372,antigenImageFileName:PA1-4560_OPRD1_P41143-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4560_OPRD1_P41143-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2156181

Product Specific Information

PA1-4560 detects delta Opioid Receptor from human, mouse, and rat samples.

PA1-4560 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~48 kDa representing the monomer form of DOR-1, and may also detect dimers or trimers as heterodimerization and homodimerization is common.

The PA1-4560 immunogen is a synthetic peptide corresponding to residues T(361) P S D G P G G G A A A(372) of human DOR-1.

Target Information

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimers patients and in the putamen in Parkinsons disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.