Thermo Fisher Scientific DFNA5 Polyclonal Antibody
DFNA5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. 합성 펩타이드를 면역원으로 사용하며, 비결합형 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from DFNA5 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2093051 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 100 µl sterile water.
- Centrifuge to remove any insoluble material.
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung, and pancreas. It exists as two alternatively spliced isoforms, designated short and long.
Defects in the DFNA5 gene cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss resulting from damage to auditory structures in the brain.
The DFNA5 gene maps to human chromosome 7, which contains over 1,000 genes and represents nearly 5% of the human genome. Mutations in genes on chromosome 7 are associated with several disorders, including Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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