Thermo Fisher Scientific DFNA5 Polyclonal Antibody
DFNA5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC에 적합합니다. Rabbit IgG로 제작되었으며, 합성 펩타이드 항원을 사용했습니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Thermo Fisher Scientific DFNA5 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:300–1:2,000
- Immunohistochemistry (IHC): 1:300–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse Dfna5h conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2261737 |
Product Specific Information
Reconstitute with 100 µL of distilled water.
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea, placenta, brain, heart, liver, lung, and pancreas. It exists as two alternatively spliced isoforms (short and long).
Defects in the DFNA5 gene cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss due to damage in brain structures that process sound.
The DFNA5 gene is located on human chromosome 7, which contains over 1,000 genes (~5% of the genome). Mutations in genes on chromosome 7 have been associated with Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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