Thermo Fisher Scientific DFNA5 Polyclonal Antibody

Thermo Fisher Scientific DFNA5 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitute with 100 µL of distilled water.

Target Information

DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung, and pancreas in two alternatively spliced isoforms (short and long).
Defects in the DFNA5 gene cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss resulting from damage to sound-receiving structures in the brain.
The DFNA5 gene maps to human chromosome 7, which contains over 1,000 genes and represents nearly 5% of the human genome. Mutations in genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.