Thermo Fisher Scientific DFNA5 Polyclonal Antibody
Thermo Fisher Scientific의 DFNA5 Polyclonal Antibody는 마우스 및 랫트 시료에서 DFNA5 단백질 검출에 적합합니다. Western blot 및 IHC에 사용 가능하며, rabbit 유래 polyclonal 항체입니다. 동결건조 형태로 제공되며, 4°C 단기 보관 또는 -20°C 장기 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 160–220 of mouse DFNA5 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: DFNA5.
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue and other organs including placenta, brain, heart, liver, lung, and pancreas, as two alternatively spliced isoforms (short and long).
Defects in DFNA5 are associated with non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss caused by damage to auditory structures in the brain.
The DFNA5 gene is located on human chromosome 7, which contains over 1,000 genes (about 5% of the human genome). Mutations in genes on this chromosome are linked to disorders such as Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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