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Thermo Fisher Scientific Coagulation Factor VIII (Cleaved form, N-term) Polyclonal Antibody
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Thermo Fisher Scientific

Thermo Fisher Scientific Coagulation Factor VIII (Cleaved form, N-term) Polyclonal Antibody

상품 한눈에 보기

인간 Coagulation Factor VIII(N-terminal, cleaved form)을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 안정화제 포함. 연구용으로만 사용 가능.

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Thermo Fisher Scientific
카테고리
Polyclonal Antibodies
판매단위
pk

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Thermo Fisher Scientific 601-960 Coagulation Factor VIII (Cleaved form, N-term) Polyclonal Antibody 100 ug pk판매 단위 pk
재고 확인 필요
421,400원VAT 포함 463,540원
실재고는 공급사 재고를 그 자리에서 확인합니다 · 확인된 값은 페이지를 벗어날 때까지 유지됩니다

Thermo Fisher Scientific · Thermo Fisher Scientific Coagulation Factor VIII (Cleaved form, N-term) Polyclonal Antibody

Applications

  • Western Blot (WB): 0.1–1 µg/mL
  • Immunohistochemistry (Paraffin) (IHC (P)): 2–10 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide corresponding to N-terminal cleavage form (VLLKRHHQR) of human FVIII protein
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS with proprietary stabilizer
Contains 0.01% sodium azide
Storage Conditions Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive control: Human colon carcinoma
  • Cellular location: Secreted, extracellular space

Target Information

Coagulation factor VIII participates in the intrinsic pathway of blood coagulation. It acts as a cofactor for factor IXa, facilitating conversion of factor X to activated factor Xa in the presence of Ca²⁺ and phospholipids.
This gene produces two alternatively spliced transcripts:

  1. Transcript variant 1 encodes a large glycoprotein (isoform a) that circulates in plasma and associates with von Willebrand factor.
  2. Transcript variant 2 encodes a smaller protein (isoform b) containing the phospholipid-binding domain essential for coagulant activity.

Defects in this gene cause Hemophilia A, a recessive X-linked coagulation disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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