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Thermo Fisher Scientific Coagulation Factor VIII (Fused form) Polyclonal Antibody
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Thermo Fisher Scientific Coagulation Factor VIII (Fused form) Polyclonal Antibody

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인체 Coagulation Factor VIII에 특이적인 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공. 연구용으로만 사용 가능하며, 혈액 응고 관련 연구에 적합.

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Thermo Fisher Scientific 601-950 Coagulation Factor VIII (Fused form) Polyclonal Antibody 100 ug pk판매 단위 pk
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422,300원VAT 포함 464,530원

Thermo Fisher Scientific · Thermo Fisher Scientific Coagulation Factor VIII (Fused form) Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 0.1–1 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 2–10 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide corresponding to fused portion of human FVIII protein surrounding HQREI domain, with depletion of cleavage terminus
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS with proprietary stabilizer
Contains 0.01% sodium azide
Storage Conditions Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive control: Human colon carcinoma
  • Cellular location: Secreted, extracellular space

Target Information

Coagulation Factor VIII participates in the intrinsic pathway of blood coagulation. It acts as a cofactor for Factor IXa, which, in the presence of Ca²⁺ and phospholipids, converts Factor X to its activated form Xa.
This gene produces two alternatively spliced transcripts:

  1. Transcript variant 1 encodes a large glycoprotein (isoform a) that circulates in plasma and associates with von Willebrand factor.
  2. Transcript variant 2 encodes a smaller protein (isoform b) consisting primarily of the phospholipid-binding domain essential for coagulant activity.

Defects in this gene result in hemophilia A, a common recessive X-linked coagulation disorder.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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