Thermo Fisher Scientific beta Amyloid Recombinant Superclonal Antibody (4HCLC)

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to react with equine, mouse, rabbit, and rat based on sequence homology.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are composed of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.

While functionally similar to polyclonal antibodies—recognizing multiple epitope sites and offering higher detection sensitivity for low-abundance targets—these recombinant antibodies have a defined mixture of light and heavy chains, ensuring batch-to-batch consistency.

Note: Formerly called “Recombinant polyclonal antibody,” this product is now rebranded as “Recombinant Superclonal™ antibody.” The physical product and performance remain unchanged.

Target Information

Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals with Alzheimer’s disease. The Abeta peptide (40–43 amino acids) is generated from the beta-amyloid precursor protein (beta APP) through sequential cleavage by beta-secretase (BACE) and gamma-secretase.

These proteolytic processes lead to the formation of extracellular beta-amyloid deposits, which are hallmarks of Alzheimer’s and related neurodegenerative disorders such as Lewy body dementia, Down’s syndrome, and cerebral amyloid angiopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.