Thermo Fisher Scientific GM-CSF Recombinant Superclonal Antibody (7HCLC)

Applications

• Western Blot (WB): 1–3 µg/mL

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They comprise multiple recombinant monoclonal antibodies, combining polyclonal-like sensitivity with monoclonal-like specificity and recombinant-level consistency.
These antibodies recognize multiple epitopes on the target, providing higher detection sensitivity for low-abundance proteins.
Each lot is produced with a defined mixture of light and heavy chains, eliminating biological variability common in traditional polyclonal antibody production.

Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. The physical product and performance remain unchanged.

Target Information

The GM-CSF gene encodes a cytokine regulating the production, differentiation, and function of macrophages and granulocytes. The active form exists as a homodimer in the extracellular space.
This gene is located in chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia.
It is part of a cluster with interleukins 4, 5, and 13, and is involved in promoting tissue inflammation.
Elevated GM-CSF levels have been observed in SARS-CoV-2 patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.