Thermo Fisher Scientific Aldolase A Recombinant Rabbit Monoclonal Antibody (21H7L6)

Applications

Western Blot (WB)

• Tested Dilution: 2.5 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 5 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, and Rabbit.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.
Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development.
Mutations in this gene are associated with Glycogen Storage Disease XII, an autosomal recessive disorder linked to hemolytic anemia. Disruption of this gene also plays a role in multiple cancer progressions. Related pseudogenes have been identified on chromosomes 3 and 10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.