Thermo Fisher Scientific ALDH1A1 Recombinant Rabbit Monoclonal Antibody (20H2L4)

Applications

Western Blot (WB)

• Tested Dilution: 1:200

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins. It is the second enzyme in the major oxidative pathway of alcohol metabolism. Two major liver isoforms—cytosolic and mitochondrial—can be distinguished by electrophoretic mobility, kinetic properties, and subcellular localization.
Most Caucasians have both isoforms, while approximately 50% of Orientals possess only the cytosolic isozyme, lacking the mitochondrial form. This absence may relate to the higher frequency of acute alcohol intoxication among Orientals compared to Caucasians.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.