Thermo Fisher Scientific Glutamine Synthetase Polyclonal Antibody
Rabbit에서 생산된 Glutamine Synthetase 폴리클로날 항체로, Western blot, IHC, ELISA에 적합합니다. 인간 Glutamine Synthetase(Residues 300-350)에서 유래한 합성 펩타이드 면역원 사용. Lyophilized 형태로 -20°C 이하 보관. 신경세포 대사 및 아스트로사이트 마커 연구에 유용.
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Thermo Fisher Scientific Glutamine Synthetase Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL |
| ELISA | 0.05–0.2 µg/mL |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-coupled synthetic peptide from within residues 300–350 of Human Glutamine Synthetase protein (Swiss Prot: P15104) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
Product Specific Information
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
Glutamine synthetase is an enzyme essential for nitrogen metabolism, catalyzing the condensation of glutamate and ammonia to form glutamine.
Its activity serves as a marker for astrocytes and plays a key role in retinal differentiation.
This antibody was developed in rabbit using a KLH-coupled synthetic peptide corresponding to residues 300–350 of human Glutamine Synthetase (Swiss Prot: P15104).
Target Information
Glutamine synthase belongs to the glutamine synthetase family.
Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase.
Glutamate serves as both a nitrogen donor and acceptor and regulates neurotransmitter metabolism.
GS activity is controlled by adenylylation and is reduced in Alzheimer’s disease and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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