Thermo Fisher Scientific HCN1 Monoclonal Antibody (RTQ 7C3), eBioscience
Mouse 및 Rat HCN1 단백질을 인식하는 RTQ 7C3 단클론 항체. Western blot에서 약 110 kDa 밴드 검출. 0.5 mg/mL 농도의 액상 형태, Affinity chromatography로 정제. 연구용으로만 사용 가능.
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Thermo Fisher Scientific HCN1 Monoclonal Antibody (RTQ 7C3), eBioscience
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rat / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RTQ 7C3 |
| Immunogen | aa 650–685 of rat HCN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802194 |
Product Specific Information
This RTQ 7C3 monoclonal antibody recognizes mouse and rat HCN1. Clone RTQ 7C3 detects a ~110 kDa band corresponding to HCN1 by Western Blot.
Applications Reported: Western blot.
Applications Tested: Western blot of mouse and rat tissue lysates. Recommended dilution ≤ 1 µg/mL.
Target Information
HCN1 belongs to the hyperpolarization-activated cation channel family, contributing to spontaneous rhythmic activity in heart and brain.
It plays a key role in motor learning and neuronal integration by cerebellar Purkinje cells, shaping autonomous neuronal activity and network oscillations.
HCN1 is highly expressed in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus.
HCN2 is abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body.
Regional specificity of HCN channels contributes to differences in neuronal pacemaker activity across brain systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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