Thermo Fisher Scientific PSMD7 Polyclonal Antibody
Thermo Fisher Scientific PSMD7 Polyclonal Antibody는 인간 PSMD7 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, Flow Cytometry에 사용 가능. KLH 결합 합성 펩타이드(267-295 aa)를 면역원으로 하며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 267–295 amino acids from the C-terminal region of human PSMD7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542130 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
Proteolytic degradation is essential for maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, receptor modulation, ion channel regulation, cell cycle, transcription, and signaling.
The ubiquitin-proteasome pathway degrades most cytosolic and nuclear proteins in eukaryotic cells, while others are degraded via the vacuolar pathway involving endosomes, lysosomes, and the endoplasmic reticulum.
The 26S proteasome is an ATP-dependent, multisubunit (~31) complex with a molecular weight of ~2.5 MDa, composed of a 20S proteolytic core and one or two 19S regulatory subunits. The 19S subunits recognize ubiquitinated proteins and facilitate their unfolding and translocation into the 20S core.
Defects in the ubiquitin-proteasome pathway are linked to several genetic diseases, including cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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