Thermo Fisher Scientific ITGA7 Polyclonal Antibody
Thermo Fisher Scientific의 ITGA7 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot에 적합합니다. Integrin alpha-7 단백질을 인식하며, 항원 친화 크로마토그래피로 정제된 고순도 항체입니다. 연구용으로 근육 관련 세포 이동 및 분화 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 926–976 of human Integrin alpha7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554059 |
Product Specific Information
This antibody detects endogenous protein at molecular weights of 25 and 129 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Integrin alpha-7 is encoded by the ITGA7 gene, mapped to chromosome 12q13.2.
It belongs to the integrin alpha chain family and forms heterodimeric complexes with beta chains.
Integrins mediate cell-cell and cell-matrix interactions, playing roles in:
- Cell migration
- Morphologic development
- Differentiation
- Metastasis
Integrin alpha-7 functions as a receptor for laminin-1, mainly expressed in skeletal and cardiac muscles.
It may be involved in differentiation and migration processes during myogenesis.
Defects in this gene are associated with congenital myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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