Thermo Fisher Scientific UCP1 Polyclonal Antibody
Thermo Fisher Scientific의 UCP1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot, IHC, ICC/IF, ELISA에 사용 가능하며, 미토콘드리아 내막 단백질 UCP1 검출에 적합합니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | 1 publication |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to amino acids 1–307 of human UCP1 (NP_068605.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914530 |
Product Specific Information
- Positive test controls: Mouse kidney, HL-60, Rat lung
- Localization: Mitochondrion inner membrane, Multi-pass membrane protein
Immunogen sequence:
MGGLTASDVH PTLGVQLFSA GIAACLADVI TFPLDTAKVR LQVQGECPTS SVIRYKGVLG TITAVVKTEG RMKLYSGLPA GLQRQISSAS LRIGLYDTVQ EFLTAGKETA PSLGSKILAG LTTGGVAVFI GQPTEVVKVR LQAQSHLHGI KPRYTGTYNA YRIIATTEGL TGLWKGTTPN LMRSVIINCT ELVTYDLMKE AFVKNNILAD DVPCHLVSAL IAGFCATAMS SPVDVVKTRF INSPPGQYKS VPNCAMKVFT NEGPTAFFKG LVPSFLRLGS WNVIMFVCFE QLKRELSKSR QTMDCAT
Target Information
Mitochondrial uncoupling proteins (UCPs) are mitochondrial anion carrier family members that separate oxidative phosphorylation from ATP synthesis, dissipating energy as heat (mitochondrial proton leak).
UCPs facilitate anion transfer between mitochondrial membranes and regulate proton flow, reducing membrane potential.
UCP1 is expressed specifically in brown adipose tissue, which functions to produce heat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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