Thermo Fisher Scientific JMJD2B Polyclonal Antibody
JMJD2B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human과 Mouse 시료에 반응합니다. Western blot 및 ELISA에 사용 가능하며, 핵 내 단백질 검출에 적합합니다. 고순도 Affinity Chromatography 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–365 of human KDM4B/JMJD2B (NP_055830.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.58 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914525 |
Product Specific Information
- Positive test controls: Mouse brain
- Subcellular location: Nucleus
- Immunogen sequence:
MGSEDHGAQN PSCKIMTFRP TMEEFKDFNK YVAYIESQGA HRAGLAKIIP PKEWKPRQTY DDIDDVVIPA PIQQVVTGQS GLFTQYNIQK KAMTVGEYRR LANSEKYCTP RHQDFDDLER KYWKNLTFVS PIYGADISGS LYDDDVAQWN IGSLRTILDM VERECGTIIE GVNTPYLYFG MWKTTFAWHT EDMDLYSINY LHFGEPKSWY AIPPEHGKRL ERLAIGFFPG SSQGCDAFLR HKMTLISPII LKKYGIPFSR ITQEAGEFMI TFPYGYHAGF NHGFNCAEST NFATLRWIDY GKVATQCTCR KDMVKISMDV FVRILQPERY ELWKQGKDLT VLDHTRPTAL TSPELSSWSA SRASL
Target Information
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a role in histone code.
Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36, nor H4 Lys-20.
Only able to demethylate trimethylated H3 Lys-9, with a weaker activity than KDM4A, KDM4C, and KDM4D.
Demethylation of Lys residue generates formaldehyde and succinate.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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