Thermo Fisher Scientific PRODH Polyclonal Antibody
Thermo Fisher Scientific의 PRODH Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 Western blot 및 ELISA에 적합합니다. 재조합 단백질(aa 321–600)을 면역원으로 사용하였으며, 미토콘드리아 매트릭스 내 PRODH 단백질 검출에 유용합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 321–600 of human PRODH (NP_057419.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914527 |
Product Specific Information
- Positive test controls: Mouse liver, Mouse kidney, Mouse heart, Rat liver, Rat kidney
- Target location: Mitochondrion matrix
Immunogen sequence:
IDSRTKLSKH LVVPNAQTGQ LEPLLSRFTE EEELQMTRML QRMDVLAKKA TEMGVRLMVD AEQTYFQPAI SRLTLEMQRK FNVEKPLIFN TYQCYLKDAY DNVTLDVELA RREGWCFGAK LVRGAYLAQE RARAAEIGYE DPINPTYEAT NAMYHRCLDY VLEELKHNAK AKVMVASHNE DTVRFALRRM EELGLHPADH QVYFGQLLGM CDQISFPLGQ AGYPVYKYVP YGPVMEVLPY LSRRALENSS LMKGTHRERQ LLWLELLRRL RTGNLFHRPA
Target Information
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation.
Defects in this gene cause hyperprolinemia type 1 and may contribute to susceptibility to schizophrenia 4 (SCZD4).
The gene is located on chromosome 22q11.21, a region associated with DiGeorge syndrome and CATCH22 syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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