Thermo Fisher Scientific SOX2 Recombinant Rat Monoclonal Antibody (Btjce), HRP

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Additional Formats

• Unconjugated
• Alexa Fluor Plus 488
• Alexa Fluor Plus 555
• Alexa Fluor Plus 594
• Alexa Fluor Plus 647
• Request custom conjugation

Product Specific Information

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. These antibodies are generated from specific genes cloned into expression vectors and expressed in vitro.
Advantages include:

• Enhanced specificity
• Lot-to-lot consistency
• Broader immunoreactivity due to larger immune repertoire

It is recommended to titrate the antibody carefully for optimal assay performance.

Target Information

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors, involved in embryonic development and cell fate determination.
It is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach.
The SOX2 gene lies within an intron of SOX2 overlapping transcript (SOX2OT).
SOX2 may act as a transcriptional activator through protein complex formation.
Mutations in SOX2 are associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.