Thermo Fisher Scientific Phospho-Synapsin 1 (Ser9) Polyclonal Antibody
Synapsin 1의 Ser9 위치에서 인산화된 형태를 특이적으로 검출하는 rabbit polyclonal antibody. WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 정제 및 안정적 저장 조건 제공.
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Thermo Fisher Scientific Phospho-Synapsin 1 (Ser9) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SYN1 (Accession P17600), corresponding to amino acid residues around phosphorylated Ser9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816295 |
Product Specific Information
Antibody detects endogenous levels of Synapsin I only when phosphorylated at Serine 9.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members share common protein domains and are implicated in synaptogenesis and modulation of neurotransmitter release, suggesting a role in neuropsychiatric diseases. Synapsin 1 regulates axonogenesis and synaptogenesis, serving as a substrate for various protein kinases. Phosphorylation may regulate its function in nerve terminals. Mutations in this gene can be associated with X-linked neuronal degenerative disorders such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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