Thermo Fisher Scientific Phospho-IGFBP3 (Ser183) Polyclonal Antibody
인간 및 생쥐 IGFBP3의 Ser183 인산화 형태를 검출하는 폴리클로날 항체. Western blot과 IHC(파라핀) 적용 가능. 고순도 액상 형태로 PBS/glycerol 버퍼에 보존. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IGFBP3 (Accession P17936), corresponding to amino acid residues around phosphorylated Ser183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816297 |
Product Specific Information
This antibody detects endogenous levels of IGFBP3 only when phosphorylated at Serine 183.
Target Information
IGFBP3 belongs to the insulin-like growth factor binding protein (IGFBP) family. The encoded protein contains both an IGFBP domain and a thyroglobulin type-I domain. It forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either IGF I or II, which circulates in plasma and prolongs the half-life of IGFs while modulating their receptor interactions. Multiple isoforms exist due to alternative splicing. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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