Thermo Fisher Scientific Phospho-JunD (Ser255) Polyclonal Antibody
Phospho-JunD (Ser255) 특이적 인식 항체로, 인산화된 JunD 단백질 검출에 적합. Western blot, IHC, ICC/IF 등 다양한 어플리케이션에 사용 가능. Rabbit polyclonal 형태로, Human, Mouse, Rat 반응성. 세포 스트레스 반응 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human JUND (Accession P17535), corresponding to amino acid residues around phosphorylated Ser255. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816294 |
Product Specific Information
This antibody detects endogenous levels of JunD only when phosphorylated at Serine 255.
Target Information
JunD is a transcription factor encoded by the JunD gene. Its transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N-terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family. Jun proteins can form dimers with Fos, ATF, and CREB family transcription factors to form the AP-1 complex, which regulates genes involved in cellular growth, proliferation, differentiation, and apoptosis. JunD also plays an important role in metabolism by modulating the IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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