Thermo Fisher Scientific BRI3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total BRI3.

Target Information

BRI3 (brain protein I3), also known as pRGR2 or I3, is a 125 amino acid multi-pass membrane protein.
The gene encoding BRI3 maps to human chromosome 7, which spans about 158 million bases, encodes over 1000 genes, and represents about 5% of the human genome.

Chromosome 7 has been linked to several conditions, including:

• Osteogenesis imperfecta
• Pendred syndrome
• Lissencephaly
• Citrullinemia
• Shwachman-Diamond syndrome

Deletions of the q arm of chromosome 7 are associated with:

• Williams-Beuren syndrome (characterized by mild mental retardation, friendliness with strangers, and elfin appearance)
• Myeloid disorders such as acute myelogenous leukemia and myelodysplasia

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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