Thermo Fisher Scientific BRI3 Polyclonal Antibody
BRI3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. Western blot 및 IHC(Paraffin) 적용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BRI3 (Accession O95415), corresponding to amino acid residues M1–A32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852997 |
Product Specific Information
Antibody detects endogenous levels of total BRI3.
Target Information
BRI3 (brain protein I3), also known as pRGR2 or I3, is a 125 amino acid multi-pass membrane protein.
The gene encoding BRI3 maps to human chromosome 7, which spans about 158 million bases, encodes over 1000 genes, and represents about 5% of the human genome.
Chromosome 7 has been linked to several conditions, including:
- Osteogenesis imperfecta
- Pendred syndrome
- Lissencephaly
- Citrullinemia
- Shwachman-Diamond syndrome
Deletions of the q arm of chromosome 7 are associated with:
- Williams-Beuren syndrome (characterized by mild mental retardation, friendliness with strangers, and elfin appearance)
- Myeloid disorders such as acute myelogenous leukemia and myelodysplasia
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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