Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), FITC
CaV3.1 단백질을 검출하기 위한 FITC 결합 단클론 항체로, 인간·마우스·랫트 반응성 보유. WB, IHC, ICC/IF에 사용 가능하며, 형광 특성은 498/517 nm. 단백질 G로 정제된 액상 형태로 4°C 암소 보관.
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Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N178A/9 |
| Immunogen | Fusion protein amino acids 2052–2172 (cytoplasmic C-terminus) of mouse Cav3.1 |
| Conjugate | FITC |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931998 |
Additional Formats
- Unconjugated (MA5-27655)
- APC (MA5-45543)
- PE (MA5-45546)
- PerCP (MA5-45545)
- Request custom conjugation available
Product Specific Information
- 1 µg/mL of MA5-45544 was sufficient for detection of Cav3.1 in 20 µg of rat brain membrane lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately <200 kDa.
- Does not cross-react with Cav3.2.
- Formerly sold as clone S178A-9.
Target Information
Voltage-dependent Ca²⁺ channels mediate Ca²⁺ entry into excitable cells upon membrane depolarization and are involved in various Ca²⁺-dependent processes such as muscle contraction, hormone or neurotransmitter release, and gene expression.
These channels are multimeric complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits.
Ca²⁺ currents are classified as L-, N-, T-, P-, Q-, and R-types.
T-type Ca²⁺ currents activate and inactivate rapidly at more negative potentials than other types, enhancing odor sensitivity by lowering spike generation thresholds in olfactory receptor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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