Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), APC
CaV3.1 단백질을 인식하는 마우스 단클론 항체로, APC 형광으로 표지되어 있습니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. Protein G로 정제된 액상 형태로 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N178A/9 |
| Immunogen | Fusion protein amino acids 2052–2172 (cytoplasmic C-terminus) of mouse Cav3.1 |
| Conjugate | APC |
| Excitation/Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931997 |
Additional Formats
- Unconjugated (MA5-27655)
- FITC (MA5-45544)
- PE (MA5-45546)
- PerCP (MA5-45545)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45543 was sufficient for detection of Cav3.1 in 20 µg of rat brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately <200 kDa. Does not cross-react with Cav3.2.
- This antibody was formerly sold as clone S178A-9.
Target Information
Voltage-dependent Ca²⁺ channels mediate calcium entry into excitable cells in response to membrane depolarization and are involved in processes such as muscle contraction, hormone and neurotransmitter release, and gene expression. These channels are multimeric complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits.
T-type calcium channels are activated and inactivated more rapidly and at more negative membrane potentials than other types, enhancing odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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