Thermo Fisher Scientific Ankyrin G Monoclonal Antibody (N106/20), FITC
Ankyrin G 단백질 검출용 FITC 결합 단클론 항체로, WB 및 ICC/IF에 적합합니다. Human, Mouse, Rat 반응성 보유하며, Protein G 정제 및 액상 형태로 제공됩니다. 4°C 암소 보관, 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N106/20 |
| Immunogen | Fusion protein of the 1000 C-terminal amino acids of human Ankyrin G (ANK-3), excluding Ankyrin repeats (aa 3377–4377) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931995 |
Additional Formats
- APC (Cat. MA5-45540)
- PerCP (Cat. MA5-45542)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45541 was sufficient for detection of Ankyrin-G in 20 µg of rat brain membrane lysate, assayed by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody. Detects approximately >200 kDa.
This antibody was formerly sold as clone S106-20.
Target Information
Ankyrin-G is expressed in various tissues including brain, where tissue-specific RNA processing produces two isoforms localized to axon initial segments and nodes of Ranvier. It is also found at epithelial cell-cell junctions and intracellular membranes. Ankyrin-G isoforms contain a serine/threonine-rich region following a globular head domain and are involved in maintaining and targeting ion channels and adhesion molecules to axon initial segments and nodes of Ranvier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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