Thermo Fisher Scientific Ankyrin G Monoclonal Antibody (N106/20), APC
Ankyrin G 단백질 검출용 APC 형광 접합 단일클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 단백질 G 정제 및 방부제 무첨가 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N106/20 |
| Immunogen | Fusion protein of 1000 C-terminal amino acids of human Ankyrin G (ANK-3/ankyrin-3), excluding Ankyrin repeats (aa 3377–4377) |
| Conjugate | APC |
| Excitation/Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931994 |
Additional Formats
- FITC (Cat. MA5-45541)
- PerCP (Cat. MA5-45542)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45540 was sufficient for detection of Ankyrin-G in 20 µg of rat brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately >200 kDa.
This antibody was formerly sold as clone S106-20.
Target Information
Ankyrin-G is expressed in various tissues, notably in the brain where tissue-specific RNA processing produces two isoforms localized at axon initial segments and nodes of Ranvier. It is also found at epithelial cell junctions and intracellular membranes.
Ankyrin-G isoforms contain a serine/threonine-rich sequence following a globular head domain and are involved in maintaining and targeting ion channels and cell adhesion molecules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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