Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI8H7), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411-amino-acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
Mutations in the NAGA gene (located on chromosome 22q13.2) cause Schindler disease (types I, II, and III), also known as NAGA deficiency. The disease manifests with varying neurological severity: type I being the most severe, type III mild-to-moderate, and type II (Kanzaki disease) characterized by mild intellectual impairment and angiokeratoma corporis diffusum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.