Thermo Fisher Scientific PXN Monoclonal Antibody (OTI6G9), TrueMAB
PXN 단백질을 인식하는 OTI6G9 클론의 단일클론 항체로, Western Blot 등 연구용에 적합. 인간, 마우스, 랫트 반응성. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험용으로 최적화됨.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G9 |
| Immunogen | Full length human recombinant protein of human PXN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL.
Tyrosine phosphorylation of paxillin is influenced by changes in cell-cell adhesion.
Paxillin associates tightly with FAK and Crk through its SH2 domain, independent of the extracellular matrix.
Initially discovered in fibroblasts, paxillin phosphorylation may also play a role during neurite extension and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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