Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI7F1), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates.
Defects in NAGA cause Schindler disease (types I, II, and III), also known as NAGA deficiency. These autosomal recessive disorders vary in neurological severity, with type I being the most severe and type II (Kanzaki disease) characterized by mild intellectual impairment and angiokeratoma corporis diffusum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.