Thermo Fisher Scientific Connexin 26 Polyclonal Antibody
Connexin 26 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS buffer에 보관하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | 27 publications |
| Immunohistochemistry (IHC) | – | 34 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 10–20 µg/mL | 5 publications |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | 20 publications |
| ELISA | 0.1–1.0 µg/mL | – |
| Immunoprecipitation (IP) | – | 2 publications |
| Miscellaneous (PubMed) | – | 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein. This sequence differs from the rat by one amino acid and from the human by two non-consecutive amino acids. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533903 |
Target Information
Gap junctions are conduits that allow direct cell-to-cell passage of small cytoplasmic molecules such as ions, metabolic intermediates, and second messengers, mediating intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial roles in these channels. Defects in GJB3 are linked to erythrokeratodermia variabilis (EKV), an autosomal dominant genodermatosis characterized by transient red patches or hyperkeratosis. Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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