Thermo Fisher Scientific ALDH3A2 Polyclonal Antibody
Mouse ALDH3A2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:2,000 희석 범위로 사용 가능. 보존제 무첨가이며 장기 보관 시 -20°C 권장. ALDH3A2 관련 연구 및 효소 기능 분석에 적합.
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Thermo Fisher Scientific ALDH3A2 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Mouse ALDH3A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788530 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Mouse ALDH3A2.
Target Information
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, which includes NAD(P)(+)-dependent enzymes catalyzing oxidation of a wide range of aliphatic and aromatic aldehydes. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation.
Aldh3A2 catalyzes oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder characterized by ichthyosis, mental retardation, and spastic diplegia. The pathogenesis is thought to result from abnormal lipid accumulation in skin and brain membranes or defective eicosanoid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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