Thermo Fisher Scientific HNF6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:300-1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to the C-terminus of the Human ONECUT1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HNF6,uniProtId:Q9UBC0-1,ncbiNodeId:9606,antigenRange:465,antigenLength:465,antigenImageFileName:PA5-81307_HNF6_Q9UBC0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-81307_HNF6_Q9UBC0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2788524

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human ONECUT1.

Target Information

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.