Thermo Fisher Scientific ALDH7A1 Recombinant Rabbit Monoclonal Antibody (101)
Recombinant rabbit monoclonal antibody specific to human ALDH7A1. Validated for ICC/IF and Flow Cytometry. High specificity and lot-to-lot consistency. Preservative-free formulation with protein A purification. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| Flow Cytometry (Flow) | 1:25–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 101 |
| Immunogen | Recombinant Human ALDH7A1 protein (Ser2–Gln511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784966 |
Available Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to large rabbit immune repertoire
This antibody has specificity for Human ALDH7A1.
Target Information
The ALDH7A1 gene encodes a member of the aldehyde dehydrogenase family, subfamily 7. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. This protein also participates in lysine catabolism within the mitochondrial matrix. It is localized in both the cytosol and mitochondria, likely due to alternative translation initiation sites. Mutations in ALDH7A1 are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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