Thermo Fisher Scientific ALDH4A1 Recombinant Rabbit Monoclonal Antibody (002)
Recombinant rabbit monoclonal antibody specific to human ALDH4A1. Validated for WB, ELISA, and IP applications. Offers high specificity, lot-to-lot consistency, and preservative-free formulation. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Human ALDH4A1 Protein (Lys25–Gln563) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784963 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to prevent contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to rabbit immune repertoire
This antibody has specificity for Human ALDH4A1.
Target Information
ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1) belongs to the aldehyde dehydrogenase family. It is a mitochondrial NAD-dependent enzyme catalyzing the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of ALDH4A1 is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of P5C and proline.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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