Thermo Fisher Scientific FGFR2 Polyclonal Antibody
FGFR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 인간 및 마우스 반응성. 액상 형태로 1 mg/mL 농도, 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 5–10 µg/mL |
| ELISA | 1:10,000–1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-FGFR2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal portion of human FGFR2 conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against human FGFR2. A BLAST analysis suggests cross-reactivity with mouse FGFR2 based on 100% homology with the immunizing sequence.
Target Information
FGFR2 is a member of the FGFR family of receptor tyrosine kinases, which regulate cellular functions such as angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, differentiation, and tissue repair.
Mutations in FGFR2 are associated with various syndromes, including Crouzon, Pfeiffer, Craniosynostosis, Apert, Jackson-Weiss, Beare-Stevenson, Saethre-Chotzen, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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