Thermo Fisher Scientific RCH1/KPNA2 Polyclonal Antibody
RCH1/KPNA2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC 및 IHC(Paraffin) 실험에 사용 가능하며, Human과 Mouse에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 475 and the C-terminus (residue 529) of Human RAG cohort 1 (Karyopherin Alpha 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan and Chimpanzee
Target Information
The import of proteins into the nucleus is a process involving at least two steps:
- Energy-independent docking of the protein to the nuclear envelope.
- Energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), typically consisting of one or two short regions of basic amino acids spaced about 10 residues apart. Proteins involved in the first step of nuclear import include importin (Xenopus) and its yeast homolog SRP1, which bind to the NLS.
KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in nuclear transport of proteins. It may also play a role in VJ recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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