Thermo Fisher Scientific PAPK (ALS2CR2) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 399-418 (SPWSELEFQFPDDKDPVWEF) of mouse PAPK conjugated to KLH at the C-terminus. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ALS2CR2,uniProtId:Q8K4T3-1,ncbiNodeId:10090,antigenRange:399-418,antigenLength:418,antigenImageFileName:28107-100UG_ALS2CR2_Q8K4T3-1_Rabbit.svg,antigenImageFileNamePDP:28107-100UG_ALS2CR2_Q8K4T3-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.0 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.