Thermo Fisher Scientific SAP30L Polyclonal Antibody
SAP30L 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며, 인간 단백질에 반응. Protein A로 정제된 액상 형태로 제공되며, PBS 버퍼에 보존제 없이 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 165–183 (VKSNKSRLDQKSEGGKQLE) of human SAP30L conjugated to KLH at the N-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
A novel TGF-beta up-regulated mRNA species, the Sin3-associated protein 30-like (SAP30L), has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein, although mutating it does not completely remove SAP30L from the nuclei. Due to its nuclear localization and close homology to SAP30, it is thought that SAP30L may play a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to silencing of proliferation-driving genes in differentiating intestinal epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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