Thermo Fisher Scientific PAPK (ALS2CR2) Polyclonal Antibody
Thermo Fisher Scientific PAPK (ALS2CR2) Polyclonal Antibody는 mouse PAPK 단백질을 특이적으로 인식하는 rabbit polyclonal 항체입니다. Western blot에 적합하며, Protein A로 정제된 액상 형태로 제공됩니다. PBS(pH 7.4)에 보존제가 없으며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 399–418 (SPWSELEFQFPDDKDPVWEF) of mouse PAPK conjugated to KLH at the C-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is part of a complex involved in activating serine/threonine kinase 11 (a master kinase regulating cell polarity and metabolism). The complex regulates the relocation of this kinase from nucleus to cytoplasm and is essential for G1 cell cycle arrest. The encoded protein can also interact with the X-linked inhibitor of apoptosis protein, enhancing anti-apoptotic activity via the JNK1 signal transduction pathway. Two pseudogenes are located on chromosomes 1 and 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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