Thermo Fisher Scientific P2RX2 Polyclonal Antibody
P2RX2 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. WB 및 IHC에 사용 가능하며, 인간, 마우스, 원숭이, 랫트에 반응합니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:3,000 | - |
| Immunohistochemistry (IHC) | 1:3,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse P2RX2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: P2RX2
Target Information
P2RX2 belongs to the ligand-gated ion channel family that opens in response to extracellular ATP. Each receptor is composed of a trimer of subunits (P2X1–7) sharing a common structure with two transmembrane domains. P2RX2 mediates synaptic transmission between neurons and from neurons to smooth muscle.
Six transcript variants encoding distinct isoforms have been identified. P2RX2 is involved in excitatory postsynaptic responses in sensory neurons, neuromuscular junction formation, hearing, taste perception, and peristalsis.
In the inner ear, P2RX2 regulates sound transduction, auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K⁺ recycling.
Diseases associated with P2RX2 include Deafness, Autosomal Dominant 41 and Dfna41 Nonsyndromic Hearing Loss and Deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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