Thermo Fisher Scientific KCNMA1 Polyclonal Antibody
KCNMA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western Blot 및 Immunohistochemistry에 사용 가능. 인간 및 비인간 영장류 반응성. 합성 펩타이드 항원 기반으로 제작되어 높은 특이성과 재현성 제공. 연구용으로만 사용.
- 카탈로그번호
- OSP00028W-100UL
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (IHC) | 1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human KCNMA1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: KCNMA1.
Target Information
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization.
This dual activation is possible because of its structure. The core of the channel, a Maxi K+ alpha homotetramer, contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry, decreasing by 5- to 10-fold the calcium concentration required to keep the pore open.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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