Thermo Fisher Scientific KCNT2 Polyclonal Antibody
KCNT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 인간, 생쥐, 랫트 반응성 확인. 합성 펩타이드 면역원 사용, 동결건조 형태로 제공되며 연구용으로만 사용됩니다.
- 카탈로그번호
- OSP00024W-100UL
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific KCNT2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 500–580 of the 4th cytoplasmic domain of Potassium channel subfamily T member 2 (KCNT2, SLICK), conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
- Specificity: KCNT2.
Target Information
Kcnt2 calcium (Ca²⁺)-activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K⁺ ions across biological membranes.
KCa channels are classified into SK, IK, and BK subtypes (small, intermediate, and big conductance).
Kcnt2 is an outward rectifying potassium channel producing rapidly activating outward rectifier K⁺ currents.
It is activated by high intracellular sodium and chloride levels, and inhibited by ATP and inhalation anesthetics such as isoflurane.
Functionally, Kcnt2 is inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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