Thermo Fisher Scientific KCNT1 Monoclonal Antibody (N3/26)
KCNT1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Human/Mouse/Rat 시료에 반응합니다. WB, IHC, ICC 등 다양한 분석에 적합하며, 단백질 G 정제 및 액상 형태로 제공됩니다. -20°C 보관, 연구용 전용 제품입니다.
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Thermo Fisher Scientific KCNT1 Monoclonal Antibody (N3/26)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N3/26 |
| Immunogen | Fusion protein amino acids 1168–1237 of rat Slo2.2 (Slack) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735247 |
Available Conjugated Formats
Product Specific Information
1 µg/mL of MA5-27609 was sufficient for detection of Slo2.2 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 140 kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick.
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
This gene encodes a sodium-activated potassium channel subunit thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause early-onset epileptic disorders such as malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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