Thermo Fisher Scientific REEP5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human REEP5 protein. Validated for IHC (paraffin) applications. Cross-reactive with human, mouse, rat, and non-human primate. Supplied as liquid, 1 mg/mL in PBS with 0.1% sodium azide. For research use only.
- 카탈로그번호
- PA534152
- 판매단위
- pk
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Applications and Tested Dilution
- Application: Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from N-Terminus of human REEP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551505 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat (100%)
Chicken (93%)
Elephant, Platypus (86%)
Target Information
REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2, or D5S346, is a 189 amino acid multi-pass membrane protein. It is thought to promote the functional cell surface expression of olfactory receptors.
REEP5 belongs to the DP1 family and is encoded by a gene on chromosome 5, which contains approximately 181 million base pairs and around 1,000 genes (about 6% of human genomic DNA).
Chromosome 5 is associated with several genetic disorders, including:
- Cockayne syndrome (ERCC8 gene)
- Familial adenomatous polyposis (APC tumor suppressor gene)
- Treacher Collins syndrome (TCOF1 gene mutations)
- Cri du chat syndrome (partial deletion of chromosome 5)
Deletion of the 5q region or entire chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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