Thermo Fisher Scientific REEP5 Polyclonal Antibody

Applications and Tested Dilution

• Application: Immunohistochemistry (Paraffin) (IHC (P))
• Tested Dilution: 2.5 µg/mL

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:
Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat (100%)
Chicken (93%)
Elephant, Platypus (86%)

Target Information

REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2, or D5S346, is a 189 amino acid multi-pass membrane protein. It is thought to promote the functional cell surface expression of olfactory receptors.
REEP5 belongs to the DP1 family and is encoded by a gene on chromosome 5, which contains approximately 181 million base pairs and around 1,000 genes (about 6% of human genomic DNA).

Chromosome 5 is associated with several genetic disorders, including:

• Cockayne syndrome (ERCC8 gene)
• Familial adenomatous polyposis (APC tumor suppressor gene)
• Treacher Collins syndrome (TCOF1 gene mutations)
• Cri du chat syndrome (partial deletion of chromosome 5)
  Deletion of the 5q region or entire chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.