
Thermo Fisher Scientific RGR Polyclonal Antibody
RGR 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 및 영장류 시료에 반응합니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 제품으로, 단기 4°C, 장기 -20°C 보관 권장됩니다.
- 카탈로그번호
- PA534154
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 1st extracellular domain of human RGR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551507 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Marmoset (100%)
Bovine, Horse, Pig (94%)
Dog, Bat, Elephant (88%)
Mouse, Rat, Hamster (81%)
Target Information
This gene encodes a putative retinal G-protein coupled receptor and is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins that bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase that catalyzes the conversion of all-trans-retinal to 11-cis-retinal, with the reverse isomerization occurring with rhodopsin in retinal photoreceptor cells. Expression is restricted to tissue adjacent to retinal photoreceptor cells, including the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP). Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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