Thermo Fisher Scientific RGR Polyclonal Antibody
RGR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, IHC(P)에서 검증됨. 인간, 말, 영장류, Xenopus에 반응하며, 항원 친화 크로마토그래피로 정제됨. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 9–17 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Horse, Human, Non-human primate, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 2nd extracellular domain of human RGR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551508 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Horse, Xenopus (100%)
Bovine (94%)
Target Information
This gene encodes a putative retinal G-protein coupled receptor, a member of the opsin subfamily of the 7-transmembrane G-protein coupled receptor 1 family.
Like other opsins that bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain.
The protein acts as a photoisomerase, catalyzing the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells.
It is exclusively expressed in tissues adjacent to retinal photoreceptor cells, including the retinal pigment epithelium and Mueller cells.
This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP).
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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